KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LEO1
All Species:
18.18
Human Site:
S551
Identified Species:
36.36
UniProt:
Q8WVC0
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WVC0
NP_620147.1
666
75404
S551
R
A
S
I
R
R
E
S
Q
Q
R
R
M
R
E
Chimpanzee
Pan troglodytes
XP_001170061
606
67985
R495
R
R
E
S
Q
Q
R
R
M
R
E
K
Q
H
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535485
665
75345
S550
R
A
S
I
R
R
E
S
Q
Q
R
R
M
R
E
Cat
Felis silvestris
Mouse
Mus musculus
Q5XJE5
667
75623
S552
R
A
S
I
R
R
E
S
Q
Q
R
R
M
R
E
Rat
Rattus norvegicus
Q641X2
678
76939
S563
R
A
S
I
R
R
E
S
Q
Q
R
R
M
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512640
354
40227
R243
R
R
E
S
Q
Q
R
R
M
R
E
K
Q
H
Q
Chicken
Gallus gallus
XP_413803
627
71376
P516
L
P
M
A
G
R
D
P
E
S
Q
R
T
E
M
Frog
Xenopus laevis
Q52KV5
703
80388
S582
R
A
S
I
R
R
E
S
Q
Q
R
R
M
R
E
Zebra Danio
Brachydanio rerio
Q6NYV9
696
76423
P550
L
N
A
G
Y
L
E
P
D
R
Y
D
E
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q94546
725
77404
K574
Q
A
M
R
N
Q
H
K
S
L
P
K
K
K
K
Honey Bee
Apis mellifera
XP_624295
603
67203
R492
E
K
L
R
M
A
M
R
V
Q
S
K
T
K
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781595
591
67675
N480
K
V
V
P
I
S
G
N
D
P
E
A
Q
R
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.9
N.A.
97.7
N.A.
93.4
92.1
N.A.
47.5
78.8
70.9
60.3
N.A.
32.5
36.3
N.A.
42.7
Protein Similarity:
100
90.9
N.A.
99
N.A.
96.5
95.5
N.A.
49.7
86.7
82
69.8
N.A.
49.3
54.9
N.A.
59.4
P-Site Identity:
100
6.6
N.A.
100
N.A.
100
100
N.A.
6.6
13.3
100
13.3
N.A.
6.6
6.6
N.A.
6.6
P-Site Similarity:
100
40
N.A.
100
N.A.
100
100
N.A.
40
33.3
100
26.6
N.A.
40
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
50
9
9
0
9
0
0
0
0
0
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
9
0
17
0
0
9
0
9
0
% D
% Glu:
9
0
17
0
0
0
50
0
9
0
25
0
9
9
50
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
9
9
0
9
0
0
0
0
0
0
0
9
% G
% His:
0
0
0
0
0
0
9
0
0
0
0
0
0
17
0
% H
% Ile:
0
0
0
42
9
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
9
9
0
0
0
0
0
9
0
0
0
34
9
17
17
% K
% Leu:
17
0
9
0
0
9
0
0
0
9
0
0
0
0
0
% L
% Met:
0
0
17
0
9
0
9
0
17
0
0
0
42
0
9
% M
% Asn:
0
9
0
0
9
0
0
9
0
0
0
0
0
0
0
% N
% Pro:
0
9
0
9
0
0
0
17
0
9
9
0
0
0
0
% P
% Gln:
9
0
0
0
17
25
0
0
42
50
9
0
25
0
17
% Q
% Arg:
59
17
0
17
42
50
17
25
0
25
42
50
0
50
0
% R
% Ser:
0
0
42
17
0
9
0
42
9
9
9
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
17
0
0
% T
% Val:
0
9
9
0
0
0
0
0
9
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
0
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _